Coronary heart disease patients with no teeth have nearly double the risk of death as those with all of their teeth, according to research published in the European Journal of Preventive Cardiology.
The study of more than 15,000 patients from 39 countries was the first to prospectively assess the relationship between tooth loss and outcomes in patients with coronary heart disease. At the beginning of the study patients completed a questionnaire about lifestyle factors (smoking, physical activity, etc.), psychosocial factors and number of teeth in five categories (26-32 [considered all teeth remaining], 20-25, 15-19, 1-14 and none).
Patients were followed for an average of 3.7 years. Associations between tooth loss and outcomes were calculated after adjusting for cardiovascular risk factors and socioeconomic status. The primary outcome was major cardiovascular events (a composite of cardiovascular death, myocardial infarction and stroke).
Patients with a high level of tooth loss were older, smokers, female, less active and more likely to have diabetes, higher blood pressure, higher body mass index and lower education.
After adjusting for cardiovascular risk factors and socioeconomic status, every increase in category of tooth loss was associated with a 6% increased risk of major cardiovascular events, a 17% increased risk of cardiovascular death, a 16% increased risk of all-cause death and a 14% increased risk of stroke.
Compared to those with all of their teeth, after adjusting for risk factors and socioeconomic status, the group with no teeth had a 27% increased risk of major cardiovascular events, an 85% increased risk of cardiovascular death, an 81% increased risk of all-cause death and a 67% increased risk of stroke.