A total of 830 companies from 59 countries participated in the International Dental Show (IDS) 2021 in a gross exhibition space of 115,000 m² in Cologne, Germany. There were 228 exhibitors and five additionally represented companies from Germany, together with 591 exhibitors and six additionally represented companies from abroad. The foreign share of company participation was 72%. Including estimates for the last day of the fair, more than 23,000 trade show visitors from 114 countries attended IDS 2021. Of these visitors, around 57% came from abroad — from Europe, especially Italy, France, the Netherlands and Eastern Europe, as well as from the Middle East and overseas.
This IDS was the first to be held in a hybrid format, so that visitors who were unable to travel owing to restrictions were still able to participate digitally. IDSconnect, the digital platform of the fair, featured 77 exhibitors from 16 countries with 88 daily contributions and 1,310 minutes of broadcast time. Oliver Frese, chief operating officer of Koelnmesse, commented on the hybrid format in a press release: “We offered the physical meeting place here in Cologne in the exhibition halls and, in addition, the digital platform IDSconnect with added opportunities for presentations and networking, which was very well received”.
Mark Stephen Pace, chairman of the executive board of the Association of the German Dental Industry said: “Optimism has returned within the international dental family. We held intensive discussions with interested visitors and most of them ultimately came to make investment decisions”.
The next IDS will take place from March 14-18, 2023.
Researchers are developing a smart dental implant that resists bacterial growth and generates its own electricity through chewing and brushing to power a tissue-rejuvenating light. The innovation could extend the usable life of an implant.
Implants represent a leap of progress over dentures or bridges, fitting much more securely and designed to last 20 years or more. But often implants fall short of that expectation, instead needing replacement in five to 10 years due to local inflammation or gum disease, necessitating a repeat of a costly and invasive procedure for patients.
Geelsu Hwang, an assistant professor in the University of Pennsylvania School of Dental Medicine, who has a background in engineering that he brings to his research on oral health issues, says: “We wanted to address this issue, and so we came up with an innovative new implant”.
The novel implant would implement two key technologies, Hwang says. One is a nanoparticle-infused material that resists bacterial colonisation. And the second is an embedded light source to conduct phototherapy, powered by the natural motions of the mouth, such as chewing or toothbrushing. In a paper in the journal ACS Applied Materials & Interfaces and a 2020 paper in the journal Advanced Healthcare Materials, Hwang and colleagues lay out their platform, which could one day be integrated not only into dental implants but other technologies, such as joint replacements.
“We wanted an implant material that could resist bacterial growth for a long time because bacterial challenges are not a one-time threat,” Hwang says.
The power-generating property of the material was sustained and in tests over time the material did not leach or harm gum tissue, and demonstrated a good level of mechanical strength.
Since periodontitis (gum disease) has been linked to systemic health conditions, including heart disease, diabetes, cancer and Alzheimer’s disease, research is continually being conducted to better understand its causes. To this end, a new Japanese study has interrogated the associations between genetic polymorphisms — the most common type of human genetic variation — oral microbiome statuses, and the development of periodontitis.
A team of researchers spread across several Japanese universities conducted the study. They first performed a cross-sectional analysis, during which they genotypically analysed 14,539 participants and carried out saliva sampling of a group of 385. Of this group, 22 individuals were retained for the study and divided into a periodontitis group and a control group based on their periodontal status.
The researchers explained that the development of infections, oral or otherwise, is affected by genetic differences among individuals, as these differences can affect susceptibility to certain pathogens and the likelihood of contracting certain diseases.
Upon examination, the research team found that the beta diversity of the microbes — the ratio between regional and local microbe species diversity — was significantly different between the periodontitis group and control group. Two bacterial families (Lactobacillaceae and Desulfobulbaceae), as well as the bacterium Porphyromonas gingivalis, were found only in the periodontitis group. However, no relationship was found to exist between genetic polymorphism and periodontal status, suggesting that the make-up of one’s oral microbiome plays a greater role in periodontal health than genes do.
The study was published the International Journal of Environmental Research and Public Health.
Mouthwashes that contain cetylpyridinium chloride (CPC) have been found to reduce by at least one thousand times the infectivity of SARS-CoV-2 (Covid-19) in vitro. Researchers in Spain tested CPC-containing mouthwashes against variants of SARS-CoV-2, including the Alpha variant, and said that such mouth rinses could constitute a cost-effective measure to aid in the reduction of viral transmission.
In the study, the researchers pointed out that cases with a higher SARS-CoV-2 viral load in the saliva are associated with higher transmission rates of the virus. They said that, if proved effective in reducing the SARS-CoV-2 viral load, the use of easily obtainable at-home oral care products could represent a globally accessible and cost-effective measure to disrupt the viral transmission chain.
The study focused on the effect of CPC, which has previously been shown to exhibit antiviral activity against viruses such as the influenza viruses. The researchers tested three Dentaid CPC-containing mouthwashes with different intended uses. The CPC-containing mouthwashes were compared with vehicles containing the same respective formulation without CPC, and it was found that the CPC-containing mouthwashes disrupted the integrity of the viral membrane and inhibited the entry of SARS-CoV-2 into target cells.
The researchers wrote: “CPC has antiviral activity against different variants of SARS-CoV-2, and this compound exerts its activity by blocking viral entry by inhibiting viral fusion on target cells. CPC acts by disrupting the integrity of the viral envelope, as previously shown for influenza virus […] and it equally affects distinct SARS-CoV-2 variants”.
The Covid-19 pandemic has resulted in the widespread adoption of videoconferencing tools in many industries, and dentistry is no exception. A new study has found that, for triage purposes and initial consultations, teledentistry has a relatively high acceptance rate among dentists and patients alike.
The study was led by an interdisciplinary team of periodontists and psychologists from King’s College London, who set out to measure dental professionals’ and patients’ attitudes towards teledentistry and how these services could be improved. Before and after video consultations between July 1 and December 14, 2020, a series of questionnaires were answered by the 228 individuals who participated.
Overall, 75.7% of the patients surveyed strongly agreed that they were comfortable accessing a dental consultation via video rather than attending an in-person dental check-up. Almost 80% of patients stated that they would recommend the video consultation. Whereas 77.4% of all respondents stated that they perceived video consultations to be either extremely or somewhat helpful prior to their appointments, this figure jumped to 87.1% after their appointments had been conducted.
There were some marked differences between the perceptions of different dental specialists regarding the helpfulness of teledentistry—perceptions that shifted once an appointment had taken place. Whereas 23.5% of periodontists believed a video appointment would not be helpful prior to it having taken place, 35.2% deemed it unhelpful post appointment. In contrast, 76.9% of restorative specialists thought, pre-appointment, that a virtual check-up would prove to be unhelpful. Post-appointment, this number dropped down to 30.8%.
A team led by University of Washington researchers has identified and classified how different people respond to the accumulation of dental plaque. Their work, recently published in the journal Proceedings of the National Academy of Sciences (PNAS), sheds new light on why some people may be more prone to serious conditions that lead to tooth loss and other problems.
Left unchecked, plaque build-up can induce gingivitis (gum disease). Gingivitis, in turn, can lead to periodontitis, a serious gum infection that damages the soft tissue and can destroy the bone that supports teeth. Not only can this result in tooth loss, but chronic inflammation can also spur other serious health consequences.
The researchers also found a previously unidentified range of inflammatory responses to bacterial accumulation in the mouth. When bacteria build-up on tooth surfaces, they generate inflammation. Previously, there were two known major oral inflammation phenotypes, or individual traits: a high clinical response; and, a low clinical response. The team identified a third phenotype, which they called ‘slow’: a delayed strong inflammatory response in the wake of the bacterial build-up.
The study revealed for the first time that subjects with low clinical response also demonstrated a low inflammatory response for a wide variety of inflammation signals. The study authors wrote that understanding the variations in gum inflammation could help better identify people at elevated risk of periodontitis. It is possible that this variation in the inflammatory response among the human population may be related to susceptibility to other chronic bacterial-associated inflammatory conditions.
A new report that could help improve how immersive technologies such as virtual reality (VR) and augmented reality (AR) are used in healthcare education and training has been published.
Prof. David Peebles, Director of the University of Huddersfield’s Centre for Cognition and Neuroscience, and Huddersfield PhD graduate Matthew Pears contributed to the report. The work also involved another PhD researcher, Yeshwanth Pulijala, and Prof. Eunice Ma.
With only a relatively small number of dental schools in the UK, the quartet visited seven dental schools in India in early 2017 to test their VR-based training materials on students.
The report argues for greater standardisation of how to use immersive technologies in healthcare training and education. As Prof. Peebles explained: “Immersive technology is becoming increasingly popular and, as the technology is advancing, it’s becoming clear that there is great potential to make training more accessible and effective”.
He continued: “Developing immersive training materials can be very time-consuming and difficult to evaluate properly. Getting surgeons and medical students to take time out to test your VR training is challenging. In our case we were lucky to have a surgeon, Prof. Ashraf Ayoub, a Professor of Oral and Maxillofacial Surgery at the University of Glasgow, who granted us permission to film a surgical procedure that was then transformed into a 3D environment to train students about situation awareness while in the operating theatre”.
Prof. Peebles hopes the work so far will provide a basis for more investigations that could help get the most from the potential that VR and immersive technology have to offer.
Tooth loss is a risk factor for cognitive impairment and dementia — and with each tooth lost, the risk of cognitive decline grows, according to a new analysis led by researchers at NYU Rory Meyers College of Nursing and published in JAMDA: The Journal of Post-Acute and Long-Term Care Medicine. However, this risk was not significant among older adults with dentures, suggesting that timely treatment with dentures may protect against cognitive decline.
Prior studies show a connection between tooth loss and diminished cognitive function, with researchers offering a range of possible explanations for this link. For one, missing teeth can lead to difficulty chewing, which may contribute to nutritional deficiencies or promote changes in the brain. A growing body of research also points to a connection between gum disease – a leading cause of tooth loss – and cognitive decline. In addition, tooth loss may reflect life-long socioeconomic disadvantages that are also risk factors for cognitive decline.
Dean’s Professor in Global Health at NYU Rory Meyers College of Nursing, Bei Wu and her colleagues conducted a meta-analysis using longitudinal studies of tooth loss and cognitive impairment. The 14 studies included in their analysis involved a total of 34,074 adults and 4,689 cases of people with diminished cognitive function.
The researchers found that adults with more tooth loss had a 1.48 times higher risk of developing cognitive impairment and 1.28 times higher risk of being diagnosed with dementia, even after controlling for other factors.
However, adults missing teeth were more likely to have cognitive impairment if they did not have dentures (23.8%) compared to those with dentures (16.9%); a further analysis revealed that the association between tooth loss and cognitive impairment was not significant when participants had dentures.
Patients who had their wisdom teeth extracted had improved tasting abilities decades after having the surgery, a new Penn Medicine, USA study published in the journal Chemical Senses found. The findings challenge the notion that removal of wisdom teeth, only has the potential for negative effects on taste, and represent one of the first studies to analyse the long-term effects of extraction on taste.
Senior author Richard L. Doty, PhD, director of the Smell and Taste Center at the University of Pennsylvania said: “Prior studies have only pointed to adverse effects on taste after extraction and it has been generally believed that those effects dissipate over time. This new study shows us that taste function can actually slightly improve between the time patients have surgery and up to 20 years later. It’s a surprising but fascinating finding that deserves further investigation to better understand why it’s enhanced and what it may mean clinically”.
Doty and co-author Dane Kim evaluated data from 1,255 patients who had undergone a chemosensory evaluation at Penn’s Smell and Taste Center over the course of 20 years. Among that group, 891 patients had received wisdom tooth extractions and 364 had not.
The “whole-mouth identification” test incorporates five different concentrations of sucrose, sodium chloride, citric acid, and caffeine. The extraction group outperformed the control group for each of the four tastes. The study suggests that people who have received extractions in the distant past experience, on average, an enhancement (typically a 3-10% improvement) in their ability to taste.
Tooth loss is often accepted as a natural part of aging, but what if there was a way to better identify those most susceptible without the need for a dental exam? New research led by investigators at the Harvard School of Dental Medicine suggests that machine learning tools can help identify those at greatest risk for tooth loss and refer them for further dental assessment in an effort to ensure early interventions to avert or delay the condition.
The study, published in PLOS ONE, compared five algorithms using a different combination of variables to screen for risk. The results showed those that factored medical characteristics and socioeconomic variables, such as race, education, arthritis, and diabetes, outperformed algorithms that relied on dental clinical indicators alone.
Study lead investigator Hawazin Elani said: “Our analysis showed that while all machine-learning models can be useful predictors of risk, those that incorporate socioeconomic variables can be especially powerful screening tools to identify those at heightened risk for tooth loss”.
The approach could be used to screen people globally and in a variety of healthcare settings, even by non-dental professionals, she added. In the study, the researchers used data comprising nearly 12,000 adults from the National Health and Nutrition Examination Survey to design and test five machine-learning algorithms and assess how well they predicted both complete and incremental tooth loss among adults based on socioeconomic, health, and medical characteristics.
The results of the analysis point to the importance of socioeconomic factors that shape risk beyond traditional clinical indicators.